تعیین ارتباط لانه‌گزینی جنین با غلظت هورمون‌ها و سیتوکین‌های انتخابی مایع فولیکولر در زنان تحت درمان به روش میکرواینجکشن (ICSI) در بخش نازایی کوثر بیمارستان شهید مطهری ارومیه

 Received: 23 Apr , 2013 Accepted: 28 Jun , 2013 Abstract Background & Aims: Concentrations of certain substances in follicular fluid (FF) may related to fertilization outcome. The study aim was to identify FF markers with which to predict embryo implantation potential.  Materials & Methods: Concentrations of selected hormones, cytokines and growth factors in FF samples obtained during assisted reproduction treatment, Intracytoplasmic Sperm Injection (ICSI) method were related with treatment outcomes.  Results: Mean concentrations of 17beta-estradiol (E2), prolactin (PRL) and insulin-like growth factor (IGF)-I were significantly higher, in treatment attempts leading to a clinical pregnancy as compared with those in which no pregnancy was established. LH, growth hormone (GH), progesterone, and interleukin-1 (IL-1) concentrations are similar in successful and unsuccessful attempts. Conclusions: Fertilization outcomes were related to FF levels of PRL, E2 and IGF-I. But LH, growth GH, progesterone, and IL-1 are not markers of success.